Which apolipoprotein serves as the structural protein of chylomicrons?

Prepare for the Clinical Chemistry and Pathologic of Biochemistry Exam with comprehensive questions, detailed explanations, and effective study strategies. Ace your test with confidence!

Multiple Choice

Which apolipoprotein serves as the structural protein of chylomicrons?

Chylomicrons use a single apolipoprotein as their scaffold to form and secrete these triglyceride-rich particles from the intestine. That structural protein is ApoB-48, a shortened form of ApoB-100 produced in enterocytes via RNA editing. ApoB-48 provides the framework for assembling dietary lipids into chylomicrons and guiding their release into the lymphatic system. In contrast, ApoB-100 is the liver-derived form that is the scaffold for VLDL, IDL, and LDL; ApoA-I and ApoA-II are major components of HDL and play roles in reverse cholesterol transport and LCAT activation. Therefore, ApoB-48 is the correct choice for the structural protein of chylomicrons.

Chylomicrons use a single apolipoprotein as their scaffold to form and secrete these triglyceride-rich particles from the intestine. That structural protein is ApoB-48, a shortened form of ApoB-100 produced in enterocytes via RNA editing. ApoB-48 provides the framework for assembling dietary lipids into chylomicrons and guiding their release into the lymphatic system. In contrast, ApoB-100 is the liver-derived form that is the scaffold for VLDL, IDL, and LDL; ApoA-I and ApoA-II are major components of HDL and play roles in reverse cholesterol transport and LCAT activation. Therefore, ApoB-48 is the correct choice for the structural protein of chylomicrons.

More practice questions