Which cancer type is associated with the highest AFP?

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Multiple Choice

Which cancer type is associated with the highest AFP?

Explanation:
Alpha-fetoprotein is a tumor marker that is most dramatically elevated in hepatocellular carcinoma. AFP is produced by fetal liver and yolk sac, and in adults its levels rise most strikingly with malignant hepatocytes in hepatocellular carcinoma, making it the strongest association among common cancers. Some germ cell tumors, such as yolk sac tumors, can also raise AFP, but the levels are typically not as high as seen with hepatocellular carcinoma. Breast cancer does not usually cause significant AFP elevation. Therefore, hepatoma is the cancer type associated with the highest AFP.

Alpha-fetoprotein is a tumor marker that is most dramatically elevated in hepatocellular carcinoma. AFP is produced by fetal liver and yolk sac, and in adults its levels rise most strikingly with malignant hepatocytes in hepatocellular carcinoma, making it the strongest association among common cancers. Some germ cell tumors, such as yolk sac tumors, can also raise AFP, but the levels are typically not as high as seen with hepatocellular carcinoma. Breast cancer does not usually cause significant AFP elevation. Therefore, hepatoma is the cancer type associated with the highest AFP.

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