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Multiple Choice

Which lipoprotein particle contains Apo-B100 as its major apolipoprotein?

ApoB-100 is the liver-derived apolipoprotein that serves as the main structural protein for several lipoproteins and as the ligand for the LDL receptor. Among common lipoprotein particles, LDL is defined by carrying ApoB-100 as its principal apolipoprotein, which enables binding to LDL receptors and delivering cholesterol to cells. Chylomicrons use ApoB-48 (intestinal form), HDL centers on ApoA-I, and while VLDL also contains ApoB-100, LDL is the classic carrier whose primary apolipoprotein is ApoB-100 and is most closely linked to receptor-mediated cholesterol delivery. Thus, the particle with Apo-B100 as its major apolipoprotein is LDL.

ApoB-100 is the liver-derived apolipoprotein that serves as the main structural protein for several lipoproteins and as the ligand for the LDL receptor. Among common lipoprotein particles, LDL is defined by carrying ApoB-100 as its principal apolipoprotein, which enables binding to LDL receptors and delivering cholesterol to cells. Chylomicrons use ApoB-48 (intestinal form), HDL centers on ApoA-I, and while VLDL also contains ApoB-100, LDL is the classic carrier whose primary apolipoprotein is ApoB-100 and is most closely linked to receptor-mediated cholesterol delivery. Thus, the particle with Apo-B100 as its major apolipoprotein is LDL.